Are there alternatives to over-the-counter diabetes-care glucose-gels for transitional neonatal hypoglycemia? Paediatrics and Child Health (Canada)Solimano, A. and Osiovich, H. and Kwan, E. and Metzger, D.L. and Everett, R.DOI: 10.1093/pch/pxaa0022021

Effects of Bisphosphonate Therapy on Bone Mineral Density in Boys with Duchenne Muscular Dystrophy. Clinical medicine insights. Endocrinology and diabetesRonsley R and Islam N and Kang M and Nadel H and Reilly C and Metzger D and Selby K and Panagiotopoulos CDOI: 10.1177/1179551420972400PubMed: 3333543712/2020

Fluid management in children with diabetic ketoacidosis. Canadian family physician Medecin de famille canadienMcGregor S and Metzger DL and Amed S and Goldman RDPubMed: 3320842111/2020

Fluid management in children with diabetic ketoacidosis,Prise en charge des liquides chez les enfants atteints d’acidocétose diabétique Canadian Family PhysicianMcGregor, S. and Metzger, D.L. and Amed, S. and Goldman, R.D.2020

Is Age a Risk Factor for Cerebral Edema in Children With Diabetic Ketoacidosis? A Literature Review Canadian Journal of DiabetesGlackin, S. and Metzger, D. and Hanas, R. and Chanoine, J.-P.DOI: 10.1016/j.jcjd.2019.04.0132020

Growth Hormone Supplementation and Psychosocial Functioning to Adult Height in Turner Syndrome: A Questionnaire Study of Participants in the Canadian Randomized Trial. Frontiers in endocrinologyRovet JF and Van Vliet GDOI: 10.3389/fendo.2019.00125PubMed: 3093085003/2019

Prevalence and Severity of High Blood Pressure Among Children Based on the 2017 American Academy of Pediatrics Guidelines JAMA PediatricsAtul K. Sharma and Daniel L. Metzger and Celia J. RoddDOI: 10.1001/jamapediatrics.2018.022306/2018

Glucose control and autonomic response during acute stress in youth with type 1 diabetes: A pilot study. Pediatric diabetesGuan L and Metzger DL and Lavoie PM and Collet JPDOI: 10.1111/pedi.12680PubMed: 2965471305/2018

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial. JAMAWriting Group for the TRIGR Study Group and Knip M and Åkerblom HK and Al Taji E and Becker D and Bruining J and Castano L and Danne T and de Beaufort C and Dosch HM and Dupre J and Wasikowa RDOI: 10.1001/jama.2017.19826PubMed: 2929707801/2018

Adherence to a pediatric diabetic ketoacidosis protocol in children presenting to a tertiary care hospital Pediatric DiabetesRonsley, R. and Islam, N. and Ronsley, C. and Metzger, D.L. and Panagiotopoulos, C.DOI: 10.1111/pedi.125562018

WHO height charts can be safely substituted when calculating BP Z-scores in a North American clinic setting Paediatrics and Child Health (Canada)Rodd, C.J. and Metzger, D.L. and Sharma, A.K.DOI: 10.1093/pch/pxx1852018

Regional differences in milk and complementary feeding patterns in infants participating in an international nutritional type 1 diabetes prevention trial Maternal & Child NutritionDOI: 10.1111/mcn.1235407/2017

Hypogonadotropic Hypogonadism in Males with Glycogen Storage Disease Type 1. JIMD reportsDOI: 10.1007/8904_2016_38PubMed: 2816024602/2017

Re: Young adult patients with diabetes presenting to a university health clinic with depression and anxiety British Columbia Medical JournalMetzger, D.L.2017

Exome Sequencing and the Management of Neurometabolic Disorders. The New England journal of medicineTarailo-Graovac M and Shyr C and Ross CJ and Horvath GA and Salvarinova R and Ye XC and Zhang LH and Bhavsar AP and Lee JJ and Drögemöller BI and Abdelsayed M and Alfadhel M and van Karnebeek CDDOI: 10.1056/nejmoa1515792PubMed: 2727656205/2016

Somatic mosaicism underlies X-linked acrogigantism syndrome in sporadic male subjects. Endocrine-related cancerDaly AF and Yuan B and Fina F and Caberg JH and Trivellin G and Rostomyan L and de Herder WW and Naves LA and Metzger D and Cuny T and Rabl W and Shah N and Jaffrain-Rea ML and Zatelli MC and Beckers ADOI: 10.1530/erc-16-0082PubMed: 2693583703/2016

Somatic mosaicism underlies X-linked acrogigantism syndrome in sporadic male subjects Endocrine-Related CancerDaly, A.F. and Yuan, B. and Fina, F. and Caberg, J.-H. and Trivellin, G. and Rostomyan, L. and De Herder, W.W. and Naves, L.A. and Metzger, D. and Cuny, T. and Rabl, W. and Shah, N. and Jaffrain-Rea, M.-L. and Chiara Zatelli, M. and Faucz, F.R. and Castermans, E. and Nanni-Metellus, I. and Lodish, M. and Muhammad, A. and Palmeira, L. and Potorac, I. and Mantovani, G. and Neggers, S.J. and Klein, M. and Barlier, A. and Liu, P. and Ouafik, L. and Bours, V. and Lupski, J.R. and Stratakis, C.A. and Beckers, A.DOI: 10.1530/ERC-16-00822016

Exome sequencing and the management of neurometabolic disorders New England Journal of MedicineTarailo-Graovac, M. and Shyr, C. and Ross, C.J. and Horvath, G.A. and Salvarinova, R. and Ye, X.C. and Zhang, L.-H. and Bhavsar, A.P. and Lee, J.J.Y. and Drögemöller, B.I. and Abdelsayed, M. and Alfadhel, M. and Armstrong, L. and Baumgartner, M.R. and Burda, P. and Connolly, M.B. and Cameron, J. and Demos, M. and Dewan, T. and Dionne, J. and Evans, A.M. and Friedman, J.M. and Garber, I. and Lewis, S. and Ling, J. and Mandal, R. and Mattman, A. and McKinnon, M. and Michoulas, A. and Metzger, D. and Ogunbayo, O.A. and Rakic, B. and Rozmus, J. and Ruben, P. and Sayson, B. and Santra, S. and Schultz, K.R. and Selby, K. and Shekel, P. and Sirrs, S. and Skrypnyk, C. and Superti-Furga, A. and Turvey, S.E. and Van Allen, M.I. and Wishart, D. and Wu, J. and Wu, J. and Zafeiriou, D. and Kluijtmans, L. and Wevers, R.A. and Eydoux, P. and Lehman, A.M. and Vallance, H. and Stockler-Ipsiroglu, S. and Sinclair, G. and Wasserman, W.W. and Van Karnebeek, C.D.DOI: 10.1056/NEJMoa15157922016

LMS tables for waist-circumference and waist-height ratio Z-scores in children aged 5-19 y in NHANES III: association with cardio-metabolic risks. Pediatric researchDOI: 10.1038/pr.2015.160PubMed: 2633176712/2015

Use of growth charts in Canada: A National Canadian Paediatric Surveillance Program survey. Paediatrics & child healthDOI: 10.1093/pch/20.4.185PubMed: 2603863405/2015

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature geneticsOnengut-Gumuscu S and Chen WM and Burren O and Cooper NJ and Quinlan AR and Mychaleckyj JC and Farber E and Bonnie JK and Szpak M and Schofield E and Achuthan P and Guo H and Rich SSDOI: 10.1038/ng.3245PubMed: 2575162403/2015

X-linked acrogigantism syndrome: clinical profile and therapeutic responses. Endocrine-related cancerBeckers A and Lodish MB and Trivellin G and Rostomyan L and Lee M and Faucz FR and Yuan B and Choong CS and Caberg JH and Verrua E and Naves LA and Cheetham TD and Young J and Lysy PA and Stratakis CADOI: 10.1530/erc-15-0038PubMed: 2571292202/2015

X-linked acrogigantism syndrome: Clinical profile and therapeutic responses Endocrine-Related CancerBeckers, A. and Lodish, M.B. and Trivellin, G. and Rostomyan, L. and Lee, M. and Faucz, F.R. and Yuan, B. and Choong, C.S. and Caberg, J.-H. and Verrua, E. and Naves, L.A. and Cheetham, T.D. and Young, J. and Lysy, P.A. and Petrossians, P. and Cotterill, A. and Shah, N.S. and Metzger, D. and Castermans, E. and Ambrosio, M.R. and Villa, C. and Strebkova, N. and Mazerkina, N. and Gaillard, S. and Barra, G.B. and Casulari, L.A. and Neggers, S.J. and Salvatori, R. and Jaffrain-Rea, M.-L. and Zacharin, M. and Santamaria, B.L. and Zacharieva, S. and Lim, E.M. and Mantovani, G. and Zatelli, M.C. and Collins, M.T. and Bonneville, J.-F. and Quezado, M. and Chittiboina, P. and Oldfield, E.H. and Bours, V. and Liu, P. and De Herder, W.W. and Pellegata, N. and Lupski, J.R. and Daly, A.F. and Stratakis, C.A.DOI: 10.1530/ERC-15-00382015

Managing type 1 diabetes in school: Recommendations for policy and practice Paediatrics and Child Health (Canada)Lawrence, S.E. and Cummings, E.A. and Pacaud, D. and Lynk, A. and Metzger, D.L.DOI: 10.1093/pch/20.1.352015

Managing type 1 diabetes in school: Recommendations for policy and practice,Prise en charge du diabète de type 1 à l'école : Recommandations de politiques et de pratiques Paediatrics and Child Health (Canada)Lawrence, S.E. and Cummings, E.A. and Pacaud, D. and Lynk, A. and Metzger, D.L.DOI: 10.1093/pch/20.1.402015

Managing type 1 diabetes in school: Recommendations for policy and practice. Paediatrics & child healthPubMed: 257226422015

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. The New England journal of medicineTrivellin G and Daly AF and Faucz FR and Yuan B and Rostomyan L and Larco DO and Schernthaner-Reiter MH and Szarek E and Leal LF and Caberg JH and Castermans E and Villa C and Stratakis CADOI: 10.1056/nejmoa1408028PubMed: 2547056912/2014

Autosomal dominant hypoparathyroidism caused by germline mutation in GNA11: phenotypic and molecular characterization. The Journal of clinical endocrinology and metabolismDOI: 10.1210/jc.2014-1029PubMed: 2482346009/2014

Hydrolyzed infant formula and early ß-cell autoimmunity: a randomized clinical trial. JAMADOI: 10.1001/jama.2014.5610PubMed: 2491525906/2014

Clinical management of youth with gender dysphoria in Vancouver. The Journal of pediatricsDOI: 10.1016/j.jpeds.2013.10.068PubMed: 2431550504/2014

Provincial disparities of growth hormone coverage for young adult survivors of paediatric brain tumours across Canada. Healthcare PolicyPubMed: 2472607602/2014

B7-H4 expression in normal and diseased human islet ß cells. PancreasDOI: 10.1097/mpa.0b013e31829695d2PubMed: 2432636701/2014

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation New England Journal of MedicineTrivellin, G. and Daly, A.F. and Faucz, F.R. and Yuan, B. and Rostomyan, L. and Larco, D.O. and Schernthaner-Reiter, M.H. and Szarek, E. and Leal, L.F. and Caberg, J.-H. and Castermans, E. and Villa, C. and Dimopoulos, A. and Chittiboina, P. and Xekouki, P. and Shah, N. and Metzger, D. and Lysy, P.A. and Ferrante, E. and Strebkova, N. and Mazerkina, N. and Zatelli, M.C. and Lodish, M. and Horvath, A. and Bertollo De Alexandre, R. and Manning, A.D. and Levy, I. and Keil, M.F. and De La Luz Sierra, M. and Palmeira, L. and Coppieters, W. and Georges, M. and Naves, L.A. and Jamar, M. and Bours, V. and Wu, T.J. and Choong, C.S. and Bertherat, J. and Chanson, P. and Kamenicky, P. and Farrell, W.E. and Barlier, A. and Quezado, M. and Bjelobaba, I. and Stojilkovic, S.S. and Wess, J. and Costanzi, S. and Liu, P. and Lupski, J.R. and Beckers, A. and Stratakis, C.A.DOI: 10.1056/NEJMoa14080282014

Extending World Health Organization weight-for-age reference curves to older children BMC PediatricsRodd, C. and Metzger, D.L. and Sharma, A. and Cummings, E. and Chanoine, J.-P. and Lawrence, S. and Palmert, M.DOI: 10.1186/1471-2431-14-322014

Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine PLoS GeneticsHolik, A.Z. and Young, M. and Krzystyniak, J. and Williams, G.T. and Metzger, D. and Shorning, B.Y. and Clarke, A.R.DOI: 10.1371/journal.pgen.10044532014

Provincial disparities of growth hormone coverage for young adult survivors of paediatric brain tumours across Canada Healthcare PolicyHasan, H. and Howard, F. and Morgan, S.G. and Metzger, D.L. and Lo, A.C. and Goddard, K. and Gill, S. and Johnson, M.DOI: 10.12927/hcpol.2014.237282014

B7-H4 expression in normal and diseased human islet ß Cells PancreasCheung, S.S.C. and Ou, D. and Metzger, D.L. and Meloche, M. and Ao, Z. and Ng, S.S.W. and Owen, D. and Warnock, G.L.DOI: 10.1097/MPA.0b013e31829695d22014

Canadian endocrinologists' views on growth hormone replacement therapy in adult survivors of pediatric brain tumors following achievement of final height British Columbia Medical JournalHasan, H. and Fuchsia Howard, A. and Metzger, D.L. and Gill, S. and Johnson, M. and Lo, A.C. and Goddard, K.2014

Canadian endocrinologists’ views on growth hormone replacement therapy in adult survivors of pediatric brain tumours following achievement of final height BC Medical Journal2014

Canadian Pediatric Endocrine Group extension to WHO growth charts: Why bother? Paediatrics & child healthPubMed: 2442169506/2013

Case 2: Pimples in prepuberty: A five-year-old with an unusual cause of facial comedones. Paediatrics & child healthDOI: 10.1093/pch/18.2.91aPubMed: 2442166402/2013

Endogenous expression of B7-H4 improves long-term murine islet allograft survival. TransplantationDOI: 10.1097/tp.0b013e318277229dPubMed: 2319215701/2013

Occurrence of slipped capital femoral epiphysis in children undergoing gonadotropin-releasing hormone agonist therapy for the treatment of central precocious puberty. Hormone research in paediatricsDOI: 10.1159/000351028PubMed: 238599502013

Canadian Pediatric Endocrine Group extension to WHO growth charts: Why bother? Paediatrics and Child Health (Canada)Lawrence, S. and Cummings, E. and Chanoine, J.-P. and Metzger, D.L. and Palmert, M. and Sharma, A. and Rodd, C.DOI: 10.1093/pch/18.6.295PubMed: 244216952013

Endogenous expression of B7-H4 improves long-term murine islet allograft survival TransplantationWang, X. and Hao, J. and Metzger, D.L. and Mui, A. and Lee, I.-F. and Akhoundsadegh, N. and Ao, Z. and Chen, L. and Ou, D. and Verchere, C.B. and Warnock, G.L.DOI: 10.1097/TP.0b013e318277229d2013

When genetic load does not correlate with phenotypic spectrum: lessons from the GnRH receptor (GNRHR). The Journal of clinical endocrinology and metabolismDOI: 10.1210/jc.2012-1264PubMed: 2274523709/2012

Generation of transplantable Beta cells for patient-specific cell therapy. International Journal of EndocrinologyDOI: 10.1155/2012/414812PubMed: 226113932012

Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival IsletsWang, X. and Hao, J. and Metzger, D.L. and Mui, A. and Lee, I.-F. and Akhoundsadegh, N. and Chen, C.L. and Ou, D. and Ao, Z. and Verchere, C.B. and Warnock, G.L.DOI: 10.4161/isl.212392012

B7-H4 induces donor-specific tolerance in mouse islet allografts Cell TransplantationWang, X. and Hao, J. and Metzger, D.L. and Mui, A. and Ao, Z. and Bruce Verchere, C. and Chen, L. and Ou, D. and Warnock, G.L.DOI: 10.3727/096368911X5827502012

B7-H4 treatment of t cells inhibits erk, jnk, p38, and akt activation PLoS ONEWang, X. and Hao, J. and Metzger, D.L. and Ao, Z. and Chen, L. and Ou, D. and Verchere, C.B. and Mui, A. and Warnock, G.L.DOI: 10.1371/journal.pone.00282322012

B7-H4 induces donor-specific tolerance in mouse islet allografts. Cell transplantationDOI: 10.3727/096368912x633815PubMed: 219298692012

Early treatment of NOD mice with B7-H4 reduces the incidence of autoimmune diabetes. DiabetesDOI: 10.2337/db11-0375PubMed: 2198458112/2011

Novel use of F-DOPA PET/CT imaging in a child with paraganglioma/pheochromocytoma syndrome. Pediatric radiologyDOI: 10.1007/s00247-011-2109-0PubMed: 2156714110/2011

Validation of diabetes case definitions using administrative claims data. Diabetic medicine : a journal of the British Diabetic AssociationDOI: 10.1111/j.1464-5491.2011.03238.xPubMed: 2139206304/2011

B7-H4 Pathway in Islet Transplantation and ß-Cell Replacement Therapies. Journal of transplantationDOI: 10.1155/2011/418902PubMed: 220289492011

Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC). Clinical trials (London, England)Hilner JE and Perdue LH and Sides EG and Pierce JJ and Wägner AM and Aldrich A and Loth A and Albret L and Wagenknecht LE and Nierras C and Akolkar B and T1DGCDOI: 10.1177/1740774510373497PubMed: 2060324807/2010

Methylation profiling in individuals with Russell-Silver syndrome. American journal of medical genetics. Part ADOI: 10.1002/ajmg.a.33204PubMed: 2008246902/2010

Diabetic ketoacidosis in children and adolescents: an update and revised treatment protocol BC Medical Journal2010

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes Nature GeneticsDOI: 10.1038/ng.38106/2009

Local expression of B7-H4 by recombinant adenovirus transduction in mouse islets prolongs allograft survival. TransplantationDOI: 10.1097/tp.0b013e318195e5faPubMed: 1930778302/2009

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse GenesisWendling, O. and Bornert, J.-M. and Chambon, P. and Metzger, D.DOI: 10.1002/dvg.204482009

Local expression of B7-H4 by recombinant adenovirus transduction in mouse islets prolongs allograft survival TransplantationWang, X. and Hao, J. and Metzger, D.L. and Mui, A. and Ao, Z. and Verchere, C.B. and Chen, L. and Ou, D. and Warnock, G.L.DOI: 10.1097/TP.0b013e318195e5fa2009

Twenty-one additional cases of familial renal glucosuria: absence of genetic heterogeneity, high prevalence of private mutations and further evidence of volume depletion. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal AssociationDOI: 10.1093/ndt/gfn386PubMed: 1862202312/2008

Study design of the Trial to Reduce IDDM in the Genetically at Risk (TRIGR) Pediatric DiabetesDOI: 10.1111/j.1399-5448.2007.00239.x06/2007

The TRIGR Trial: Testing the Potential Link between Weaning Diet and Type 1 Diabetes Immunology, Endocrine & Metabolic Agents in Medicinal ChemistryDOI: 10.2174/18715220778083231506/2007

Skewed X-chromosome inactivation is associated with primary but not secondary ovarian failure. American journal of medical genetics. Part ADOI: 10.1002/ajmg.a.31679PubMed: 1743189205/2007

Autosomal dominant pseudohypoaldosteronism type 1: mechanisms, evidence for neonatal lethality, and phenotypic expression in adults. Journal of the American Society of Nephrology : JASNDOI: 10.1681/asn.2005111188PubMed: 1661171305/2006

Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proceedings of the National Academy of Sciences of the United States of AmericaDOI: 10.1073/pnas.0600962103PubMed: 1660683604/2006

Suppression of human T-cell responses to beta-cells by activation of B7-H4 pathway. Cell transplantationDOI: 10.3727/000000006783981837PubMed: 288718682006

Autosomal dominant pseudohypoaldosteronism type 1: Mechanisms, evidence for neonatal lethality, and phenotypic expression in adults Journal of the American Society of NephrologyGeller, D.S. and Zhang, J. and Zennaro, M.-C. and Vallo-Boado, A. and Rodriguez-Soriano, J. and Furu, L. and Haws, R. and Metzger, D. and Botelho, B. and Karaviti, L. and Haqq, A.M. and Corey, H. and Janssens, S. and Corvol, P. and Lifton, R.P.DOI: 10.1681/ASN.20051111882006

Novel TRPM6 mutations in 21 families with primary hypomagnesemia and secondary hypocalcemia. Journal of the American Society of Nephrology : JASNDOI: 10.1681/asn.2004110989PubMed: 1610757810/2005

Regulation of TNF-related apoptosis-inducing ligand-mediated death-signal pathway in human beta cells by Fas-associated death domain and nuclear factor kappaB. Human immunologyDOI: 10.1016/j.humimm.2005.03.009PubMed: 1611202707/2005

Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci. The Journal of clinical endocrinology and metabolismDOI: 10.1210/jc.2005-0572PubMed: 1587011907/2005

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1. Diabetes careDOI: 10.2337/diacare.28.5.1068PubMed: 1585556905/2005

Tumor necrosis factor-related apoptosis-inducing ligand and CD56 expression in patients with type 1 diabetes mellitus. PancreasDOI: 10.1097/01.mpa.0000148515.77497.4bPubMed: 1571413203/2005

Oculorespiratory syndrome after influenza immunization in children. The Pediatric infectious disease journalDOI: 10.1097/01.inf.0000148924.89558.d5PubMed: 1566571201/2005

Synergistic inhibition of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human pancreatic ß cells by Bcl-2 and X-linked inhibitor of apoptosis Human ImmunologyOu, D. and Wang, X. and Metzger, D.L. and James, R.F.L. and Pozzilli, P. and Plesner, A. and Korneluk, R.G. and Verchere, C.B. and Tingle, A.J.DOI: 10.1016/j.humimm.2004.12.0022005

Novel TRPM6 mutations in 21 families with primary hypomagnesemia and secondary hypocalcemia Journal of the American Society of NephrologySchlingmann, K.P. and Sassen, M.C. and Weber, S. and Pechmann, U. and Kusch, K. and Pelken, L. and Lotan, D. and Syrrou, M. and Prebble, J.J. and Cole, D.E.C. and Metzger, D.L. and Rahman, S. and Tajima, T. and Shu, S.-G. and Waldegger, S. and Seyberth, H.W. and Konrad, M.DOI: 10.1681/ASN.20041109892005

Long on QT and low on calcium. Cardiology in the youngDOI: 10.1017/s1047951104006134PubMed: 1568000412/2004

Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY). Clinical and investigative medicine. Medecine clinique et experimentalePubMed: 1530580506/2004

Addison’s disease in a child with systemic lupus erythematosus Pediatric Rheumatology Online Journal2004

Long on QT and low on calcium Cardiology in the YoungBradley, T.J. and Metzger, D.L. and Sanatani, S.DOI: 10.1017/S10479511040061342004

Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY) Clinical and Investigative MedicineMcKinney, J.L. and Cao, H. and Robinson, J.F. and Metzger, D.L. and Cummings, E. and Riddell, D.C. and Sanderson, S.R. and Pacaud, D. and Ho, J. and Hegele, R.A.2004

Current approaches to the prevention of type 1 diabetes British Columbia Medical JournalMetzger, D.L.2004

Current approaches to the prevention of type 1 diabetes BC Medical Journal2004

Telephone contact by a diabetes nurse educator improves hemoglobin A1c in adolescents with poorly controlled type 1 diabetes: a randomized controlled trial Canadian Journal of Diabetes2003

Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis Biology of ReproductionWeber, P. and Schuler, M. and Gérard, C. and Mark, M. and Metzger, D. and Chambon, P.DOI: 10.1095/biolreprod.102.0058012003

Weekly Telephone Contact by a Diabetes Educator in Adolescents with Type 1 Diabetes Canadian Journal of DiabetesPanagiotopoulos, C. and Preston, J.M. and Stewart, L.L. and Metzger, D.L. and Chanoine, J.-P.2003

TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell destruction. DiabetologiaDOI: 10.1007/s00125-002-0926-2PubMed: 1248895712/2002

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY). Human mutationDOI: 10.1002/humu.9090PubMed: 1244228012/2002

Effects of insulin in relatives of patients with type 1 diabetes mellitus. The New England journal of medicineDOI: 10.1056/nejmoa012350PubMed: 1203714705/2002

beta-cell antigen-specific CD56(+) NKT cells from type 1 diabetic patients: autoaggressive effector T cells damage human CD56(+) beta cells by HLA-restricted and non-HLA-restricted pathways. Human immunologyDOI: 10.1016/s0198-8859(02)00372-5PubMed: 1203940704/2002

ß-cell antigen-specific CD56+ NKT cells from type 1 diabetic patients: Autoaggressive effector T cells damage human CD56+ ß cells by HLA-restricted and non-HLA-restricted pathways Human ImmunologyOu, D. and Metzger, D.L. and Wang, X. and Pozzilli, P. and Tingle, A.J.DOI: 10.1016/S0198-8859(02)00372-52002

Nine novel mutations in NR0B1 (DAX1) causing adrenal hypoplasia congenita. Human mutationDOI: 10.1002/humu.1236PubMed: 1174885212/2001

Spectrum of mutations of the AAAS gene in Allgrove syndrome: lack of mutations in six kindreds with isolated resistance to corticotropin. The Journal of clinical endocrinology and metabolismDOI: 10.1210/jc.86.11.5433PubMed: 1170171811/2001

High prevalence of celiac disease in patients with type 1 diabetes detected by antibodies to endomysium and tissue transglutaminase. Canadian journal of gastroenterology = Journal canadien de gastroenterologieDOI: 10.1155/2001/640796PubMed: 1138129605/2001

Spectrum of mutations of the AAAS gene in allgrove syndrome: Lack of mutations in six kindreds with isolated resistance to corticotropin Journal of Clinical Endocrinology and MetabolismSandrini, F. and Farmakidis, C. and Kirschner, L.S. and Wu, S.-M. and Tullio-Pelet, A. and Lyonnet, S. and Metzger, D.L. and Bourdony, C.J. and Tiosano, D. and Chan, W.-Y. and Stratakis, C.A.DOI: 10.1210/jcem.86.11.80372001

Increased prevalence of celiac disease in girls with Turner syndrome detected using antibodies to endomysium and tissue transglutaminase. Canadian journal of gastroenterology = Journal canadien de gastroenterologieDOI: 10.1155/2000/172914PubMed: 1112518012/2000

Cross-reactive rubella virus and glutamic acid decarboxylase (65 and 67) protein determinants recognised by T cells of patients with type I diabetes mellitus. DiabetologiaDOI: 10.1007/s001250051373PubMed: 1090712106/2000

Erratum: Antenatal treatment for classic 21-hydroxylase forms of congenital adrenal hyperplasia and the issue (Genetics in Medicine (1999)) Genetics in MedicineTravitz, J. and Metzger, D.2000

Cross-reactive rubella virus and glutamic acid decarboxylase (65 and 67) protein determinants recognised by T cells of patients with Type I diabetes mellitus DiabetologiaOu, D. and Mitchell, L.A. and Metzger, D.L. and Gillam, S. and Tingle, A.J.2000

CD4+ and CD8+ T-cell clones from congenital rubella syndrome patients with IDDM recognize overlapping GAD65 protein epitopes. Implications for HLA class I and II allelic linkage to disease susceptibility. Human immunologyDOI: 10.1016/s0198-8859(99)00037-3PubMed: 1043931108/1999

Sex-Steroid—Hormone Modulation of the Somatotropic Axis During Normal Male Puberty Sex-Steroid Interactions with Growth HormoneDaniel L. Metzger and James R. KerriganDOI: 10.1007/978-1-4612-1546-2_41999

CD4+ and CD8+ T-cell clones from congenital Rubella syndrome patients with IDDM recognize overlapping GAD65 protein epitopes: Implications for HLA class I and II allelic linkage to disease susceptibility Human ImmunologyOu, D. and Jonsen, L.A. and Metzger, D.L. and Tingle, A.J.DOI: 10.1016/S0198-8859(99)00037-31999

Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor a Molecular and Cellular BiologyEndoh, H. and Maruyama, K. and Masuhiro, Y. and Kobayashi, Y. and Goto, M. and Tai, H. and Yanagisawa, J. and Metzger, D. and Hashimoto, S. and Kato, S.DOI: 10.1128/mcb.19.8.53631999

Antenatal treatment for classic 21-hydroxylase forms of congenital adrenal hyperplasia and the issues. Genetics in medicine : official journal of the American College of Medical GeneticsPubMed: 112566771999

A provincial protocol for the treatment of diabetic ketoacidosis in children BC Medical Journal1998

Estrogen and testosterone, but not a nonaromatizable androgen, direct network integration of the hypothalamo-somatotrope (growth hormone)-insulin-like growth factor I axis in the human: evidence from pubertal pathophysiology and sex-steroid hormone replacement. The Journal of Clinical Endocrinology and MetabolismDOI: 10.1210/jcem.82.10.4317PubMed: 932937810/1997

The short-term infusion of ovine corticotropin-releasing hormone does not alter luteinizing hormone concentrations in young adult men. The Journal of Clinical Endocrinology and MetabolismDOI: 10.1210/jcem.82.2.3782PubMed: 902427902/1997

The short-term infusion of ovine corticotropin-releasing hormone does not alter luteinizing hormone concentrations in young adult men Journal of Clinical Endocrinology and MetabolismMetzger, D.L. and Kerrigan, J.R. and Rogol, A.D.DOI: 10.1210/jc.82.2.6971997

Estrogen and testosterone, but not a nonaromatizable androgen, direct network integration of the hypothalamo-somatotrope (growth homone)-insulin- like growth factor I axis in the human: Evidence from pubertal pathophysiology and sex-steroid hormone replacement Journal of Clinical Endocrinology and MetabolismVeldhuis, J.D. and Metzger, D.L. and Martha Jr., P.M. and Mauras, N. and Kerrigan, J.R. and Keenan, B. and Rogol, A.D. and Pincus, S.M.DOI: 10.1210/jc.82.10.34141997

Estrogen and diclofenac sodium therapy in a prepubertal female with idiopathic juvenile osteoporosis. Journal of pediatric endocrinology & metabolism : JPEMDOI: 10.1515/jpem.1995.8.2.135PubMed: 75847081995

Estrogen and Diclofenac Sodium Therapy in a Prepubertal Female with Idiopathic Juvenile Osteoporosis Journal of Pediatric Endocrinology and MetabolismWright, N.M. and Key, L.L. and Metzger, D.L.DOI: 10.1515/JPEM.1995.8.2.1351995

Gonadal steroid hormone regulation of the somatotropic axis during puberty in humans Mechanisms of androgen and estrogen action. Trends in endocrinology and metabolism: TEMDOI: 10.1016/1043-2760(94)p3204-kPubMed: 1840722109/1994

Estrogen receptor blockade with tamoxifen diminishes growth hormone secretion in boys: evidence for a stimulatory role of endogenous estrogens during male adolescence. The Journal of clinical endocrinology and metabolismDOI: 10.1210/jcem.79.2.8045971PubMed: 804597108/1994

Radiological case of the month. Case 2. Untreated chronic lymphocytic thyroiditis presenting as a pituitary mass and secondary hypocortisolism. Archives of pediatrics & adolescent medicineDOI: 10.1001/archpedi.1994.02170070059010PubMed: 801962607/1994

The hepatopulmonary syndrome masquerading as pulmonary Langerhans-cell histiocytosis. Hepatopulmonary Syndrome Study Group. Annals of internal medicineDOI: 10.7326/0003-4819-121-1-199407010-00006PubMed: 819834507/1994

The hepatopulmonary syndrome masquerading as pulmonary Langerhans-cell histiocytosis Annals of Internal MedicineCaldwell, S.H. and Brantley, K. and Dent, J. and Keeley, R.C. and Pruett, T. and Angle, J.F. and Gaffey, M. and Waldron, P. and Metzger, D.L. and Stevenson, W.C. and Ishitani, M. and Dickson, R.C. and Dye, K.R.1994

Gonadal steroid hormone regulation of the somatotropic axis during puberty in humans. Mechanisms of androgen and estrogen action Trends in Endocrinology and MetabolismMetzger, D.L. and Kerrigan, J.R. and Rogol, A.D.DOI: 10.1016/1043-2760(94)P3204-K1994

Cholinergic and opioid involvement in release of growth hormone during exercise and recovery. Journal of applied physiology (Bethesda, Md. : 1985)PubMed: 822649308/1993

Characterization of pulsatile secretion and clearance of plasma cortisol in premature and term neonates using deconvolution analysis. The Journal of Clinical Endocrinology and MetabolismDOI: 10.1210/jcem.77.2.8345052PubMed: 834505208/1993

Permanent neonatal diabetes mellitus and pancreatic exocrine insufficiency resulting from congenital pancreatic agenesis. American journal of diseases of children (1960)PubMed: 850682106/1993

Alterations in the neuroendocrine control of growth hormone secretion in the uremic rat. Kidney internationalDOI: 10.1038/ki.1993.146PubMed: 809963305/1993

Androgen receptor blockade with flutamide enhances growth hormone secretion in late pubertal males: evidence for independent actions of estrogen and androgen. The Journal of clinical endocrinology and metabolismDOI: 10.1210/jcem.76.5.8496305PubMed: 849630505/1993

Cholinergic and opioid involvement in release of growth hormone during exercise and recovery Journal of Applied PhysiologyThompson, D.L. and Weltman, J.Y. and Rogol, A.D. and Metzger, D.L. and Veldhuis, J.D. and Weltman, A.1993

Permanent Neonatal Diabetes Mellitus and Pancreatic Exocrine Insufficiency Resulting From Congenital Pancreatic Agenesis American Journal of Diseases of ChildrenWright, N.M. and Metzger, D.L. and Borowitz, S.M. and Clarke, W.L.DOI: 10.1001/archpedi.1993.021603000130051993